Ingredient Evidence Review
Caffeine (slow-release microencapsulated)
Caffeine anhydrous (sustained-release microcapsule)
Last updated 2026-05-19 · 3 primary citations
Mechanism
Caffeine blocks adenosine, the molecule that builds up over your waking hours and makes you sleepy. Standard caffeine spikes and falls off in 4 hours. The slow-release form keeps you alert across a full 8–12 hour shift without the second-hour jitter or the fifth-hour crash. Paired with L-theanine, the result is steady focus rather than wired-and-tired.
Why we use it
Sleep-medicine guidelines support caffeine for shift workers because it works. The problem is the delivery curve — immediate-release leaves you crashing mid-shift. The slow-release form is engineered specifically for sustained vigilance.
How we dose it
Hericea uses 100 mg per serving (per On-Shift stick pack). The clinical trial range that anchors this dose is 100–200 mg/day.
100 mg of caffeine — about a single cup of coffee — but encapsulated in a slow-release coating so it dribbles into the bloodstream over 4+ hours instead of spiking once and crashing.
Quality & sourcing
Slow-release microencapsulated caffeine anhydrous; sustained release ≥4hr. NSF Annex C permitted.
SR microencapsulation tech; not immediate-release powder.
Cautions
- consult physicianAvoid if pregnant, on stimulants, or with arrhythmias.
- informationalAvoid within 6hr of intended sleep.
Primary literature
Haskell CF et al. (2008)
Biol PsycholRCT
Caffeine + L-theanine improved attention and reaction time more than caffeine alone in healthy adults.
The foundational evidence for pairing caffeine with theanine — exactly what the AM stick does for sustained shift alertness.
PMID 18006208
Ker K et al. (2010)
Cochrane Database Syst RevCochrane meta-analysis
Caffeine reduced shift-work errors and improved vigilance vs placebo across pooled trials.
Highest tier of evidence (Cochrane review) for the exact use case — preventing errors on shift.
PMID 20464731
McLellan TM et al. (2016)
Neurosci Biobehav RevReview
Reviewed military and operational evidence: caffeine reliably restores cognitive performance during sleep deprivation.
Most relevant comparator group — operational shift workers, not coffee-drinkers.
PMID 27612937