Stay sharp
for the decades ahead.

Hericium erinaceus

Lion's Mane contains compounds (hericenones) that signal your brain to make more nerve growth factor — a kind of internal fertilizer that keeps brain cells maintained and connected. It's the only food known to safely turn that signal up, which is why it anchors a stack built for an aging brain.

Hericium erinaceus HeG-strain CNS-penetrant fraction

Lion's Mane has two families of brain-active compounds. Hericenones (in the row above) work on one growth signal; erinacines work on a different, complementary one called BDNF — and erinacine A is special because it crosses directly into the brain, where most compounds can't.

Phosphatidylserine (sunflower-derived)

Phosphatidylserine is a fat that sits in the outer wall of every brain cell — it's what lets signals pass cleanly from one cell to the next. Stress and aging deplete it, and restoring it has been shown to support memory and to blunt the cortisol spike that stress causes.

Cytidine 5'-diphosphocholine

Your brain uses a chemical called acetylcholine to form and recall memories. Citicoline is the raw material your brain needs to make it — and as we age, supply drops, so this delivers it directly. Cognizin® is the specific patented form used in the clinical trials.

Pyrroloquinoline quinone (reduced form)

PQQ is a small molecule that signals your cells to grow new mitochondria — the cellular power plants that decline with age. The most recent human trial showed it specifically increased brain oxygen levels and improved memory testing in adults already experiencing cognitive decline.

Re-esterified triglyceride DHA + EPA

DHA is the main building block of your brain's cell walls — roughly 30% of your brain is literally made of it, and your body can't manufacture it. EPA is its anti-inflammatory partner. Together they keep brain cells flexible and calm the low-grade inflammation that builds with age.

6S-5-methyltetrahydrofolate glucosamine salt

Folate is the raw material your body uses to keep nerve cells healthy and to clear a byproduct called homocysteine, which accelerates brain shrinkage when it builds up. We use the already-activated form so it works even for the 30–40% of people whose genetics make ordinary folic acid hard to use.

Methylcobalamin

B12 maintains the protective insulation around your nerve fibers and works as a pair with folate to keep brain-aging markers in check. Deficiency is one of the most common — and most missed — causes of brain fog and fatigue after 50.

Pyridoxal-5-phosphate

B6 is what your body uses to make the mood and motivation chemicals dopamine and serotonin, and it's the third partner — with folate and B12 — in clearing the brain-aging byproduct homocysteine. The trio only works as a set.

Ganoderma lucidum

Reishi is the most-studied calming mushroom. Two compound families do the work: long-chain sugars (beta-glucans) support falling asleep, and bitter compounds (triterpenes) help quiet the stress-hormone response. You need both extractions to get both effects.

Magnesium L-threonate

Most magnesium never makes it from your stomach into your brain. Magtein® uses a special carrier (L-threonate) that gets it across the blood-brain barrier — and brain magnesium is required for the deep, restorative sleep and overnight synapse repair that thin out with age.

Glycine (amino acid)

Falling asleep depends on your body cooling down by about a degree. Glycine triggers that cool-down by opening small blood vessels in your hands and feet to release heat, and it quiets the brain's arousal signals — so you fall asleep faster and spend longer in deep sleep.

N-acetyl-L-cysteine

Your body's most important built-in antioxidant is glutathione, and the limiting ingredient for making it is an amino acid called cysteine. NAC is the cleanest, most-studied way to deliver that cysteine — it pairs with the glycine in this same packet, the other half of the recipe.

Urolithin A (ellagitannin-derived gut metabolite)

Inside every cell are tiny power plants called mitochondria that wear out with age. Urolithin A triggers your cells to recycle the worn-out ones — a cleanup most people's gut bacteria can't kick off on their own. The clinical trials so far show measurable gains in muscle endurance.

L-ergothioneine

Ergothioneine is an antioxidant your body can't make (so you have to eat it) but actively goes out of its way to absorb and ferry into tissues — especially the brain, where it collects inside the cell's power plants. Falling blood levels are an early warning sign of cognitive decline.

Sulforaphane (broccoli seed extract)

Sulforaphane is the compound that gives broccoli sprouts their reputation. It switches on your body's main antioxidant defense gene (called Nrf2) — flipping a master switch that produces dozens of protective enzymes at once. Especially relevant for brain inflammation and the cellular damage that accumulates with age.

Curcuma longa rhizome extract (SLCP complex)

Curcumin is the active compound in turmeric. It calms low-grade inflammation that drives brain fog. The hard part is absorption; Longvida® is engineered specifically to fix that. Used in the published 18-month brain-imaging trial.

Pyrroloquinoline quinone (reduced form, PM)

Same PQQ as the morning row, taken again in the evening. Mitochondrial growth happens around the clock; cell-energy decline is one of the deepest changes in the 55+ brain. We dose PQQ on both ends of the day to sustain the signal.

Lithium orotate (orotate salt form)

Lithium is a naturally occurring mineral your body absorbs in trace amounts from drinking water and certain foods. At nutritional doses it supports brain-cell wiring; a major 2025 Nature paper showed running low on lithium is one of the earliest changes detectable before Alzheimer's.